Drug therapy: Sorafenib

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منابع مشابه

Biomarkers and Personalized Sorafenib Therapy

Compared with other types of cancer, hepatocellular carcinoma (HCC) is highly heterogeneous because of the intrinsic diversity in its pathogenesis, molecular heterogeneity, its multicentric occurrence, and its etiology, among others. Until now, locoregional therapies such as resection, ablation, and transarterial chemoembolization (TACE) have been performed extensively to treat HCC because the ...

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Biomarkers and Personalized Sorafenib Therapy

Compared with other types of cancer, hepatocellular carcinoma (HCC) is highly heterogeneous because of the intrinsic diversity in its pathogenesis, molecular heterogeneity, its multicentric occurrence, and its etiology, among others. Until now, locoregional therapies such as resection, ablation, and transarterial chemoembolization (TACE) have been performed extensively to treat HCC because the ...

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Biomarkers and Personalized Sorafenib Therapy

Compared with other types of cancer, hepatocellular carcinoma (HCC) is highly heterogeneous because of the intrinsic diversity in its pathogenesis, molecular heterogeneity, its multicentric occurrence, and its etiology, among others. Until now, locoregional therapies such as resection, ablation, and transarterial chemoembolization (TACE) have been performed extensively to treat HCC because the ...

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Biomarkers and Personalized Sorafenib Therapy

Compared with other types of cancer, hepatocellular carcinoma (HCC) is highly heterogeneous because of the intrinsic diversity in its pathogenesis, molecular heterogeneity, its multicentric occurrence, and its etiology, among others. Until now, locoregional therapies such as resection, ablation, and transarterial chemoembolization (TACE) have been performed extensively to treat HCC because the ...

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Sorafenib therapy decreases the clearance of thyrotropin.

OBJECTIVE Thyroid function abnormalities are common during treatment with tyrosine kinase inhibitors such as sorafenib. Suggested causes are direct effects on thyroid tissue and increased extrathyroidal metabolism of serum thyroxine and 3,5,3-triiodothyronine. We postulated that tyrosine kinase inhibitors may affect the peripheral metabolism of TSH as well. The effect of sorafenib on TSH cleara...

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ژورنال

عنوان ژورنال: Hepatology

سال: 2010

ISSN: 0270-9139

DOI: 10.1002/hep.23676